Sakitamiwa Classification ((new)) [VALIDATED • EDITION]

Hamartomas and overgrowth syndromes

A thin, white layer is still visible, but the ulcer becomes shallower and smaller. Regenerative epithelium begins to appear, giving a "reddish" look to the shrinking margin.

The Active Stage represents the acute phase of a peptic or iatrogenic ulcer. sakitamiwa classification

The is the global clinical standard for staging gastric and peptic ulcers. Developed in 1971 by Japanese gastroenterologists Sakita and Miwa, this six-stage endoscopic framework organizes the life cycle of an ulcer into three overarching macro-stages: Active (A) , Healing (H) , and Scarring (S) .

The Sakitamiwa virus was first isolated in the Tana River County of Kenya in late 2019. Early case fatality rates (CFRs) exceeded 34%, largely due to inconsistent staging. Physicians in Mombasa and Garissa used disparate criteria: some relied on platelet counts, others on bleeding manifestations, and a minority on RT-PCR cycle thresholds. In response, Dr. Amina Sakitamiwa (b. 1975), a Kenyan virologist and epidemiologist, led a Delphi consensus process involving 120 experts from 14 nations. The resulting Sakitamiwa Classification was published in the Lancet Infectious Diseases (April 2021) and has since been adopted by the WHO as the official staging system for SKTV. Hamartomas and overgrowth syndromes A thin, white layer

This is the final stage where the ulcer has effectively closed.

The ulcer base is covered with a thick white slough. The surrounding mucosa is intensely swollen (edematous) and red. No regenerative epithelium (new skin) is visible. A2 (Active-2): The is the global clinical standard for staging

The Healing Stage marks the body's successful structural defense and repair response.

The ulcer is deep, and the base is covered with a thick white or yellowish slough (exudate). The surrounding mucosa is typically red and swollen (edematous).

By providing a clear, chronological roadmap of ulcer development, the Sakita-Miwa classification remains a "gold standard" in endoscopic reporting. It bridges the gap between a single visual observation and a comprehensive treatment plan, ensuring that patients receive care tailored to the specific biological state of their condition. specific treatments typically prescribed for each of these stages?